Port Salerno is an unincorporated community in Martin County, south of Stuart near the St. Lucie Inlet. The Manatee Pocket harbor shelters fishing boats, marinas and waterfront restaurants, giving the area a working-waterfront feel. Nearby parks and the Indian River Lagoon invite boating and fishing. US 1 and Cove Road connect to Stuart and Hobe Sound. Homes include waterfront cottages, condos, mobile home communities and single-family neighborhoods.